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1.
J Bras Pneumol ; 47(1): e20190402, 2021.
Artigo em Inglês, Português | MEDLINE | ID: mdl-33439961

RESUMO

OBJECTIVE: To evaluate third- and sixth-year medical students in Brazil in terms of their knowledge of and attitudes toward the WHO MPOWER policies to reduce tobacco use. METHODS: The WHO Global Health Professions Student Survey was applied in five cohorts of medical students evaluated in their third and sixth years of medical school, between 2008 and 2015. Comparisons were drawn between the two years of medical school in terms of the proportions of students who experimented with or used tobacco products in the last 30 days prior to the survey; knowledge of and compliance with smoke-free policies on the university campus; formal training on smoking cessation strategies; and self-recognition as role models for patients/society. RESULTS: Of the 943 students who completed the survey, approximately 6% had smoked cigarettes in the last 30 days prior to the survey. Comparing the third and sixth years of medical school, we observed a significant increase in the proportion of students who were knowledgeable about smoking cessation strategies (22.74% vs. 95.84%; p < 0.001) and in that of those who recognized their role as models for patients/society (84.5% vs. 89.7%; p = 0.023). Student knowledge of the smoking policies on the university campus was associated with an increase in self-recognition as role models (adjusted absolute difference = 6.7%; adjusted p = 0.050). CONCLUSIONS: Knowledge of smoking cessation strategies and self-recognition as role models for patients/society increase over the course of medical school and are associated with the implementation of smoke-free policies.


Assuntos
Estudantes de Medicina , Atitude , Brasil , Humanos , Uso de Tabaco , Organização Mundial da Saúde
2.
J Bras Pneumol ; 43(3): 202-207, 2017.
Artigo em Inglês, Português | MEDLINE | ID: mdl-28746531

RESUMO

OBJECTIVE:: To determine the level of agreement with effective tobacco control measures recommended by the World Health Organization and to assess the attitudes toward, knowledge of, and beliefs regarding smoking among third-year medical students at University of São Paulo School of Medicine, located in the city of São Paulo, Brazil. METHODS:: Between 2008 and 2012, all third-year medical students were invited to complete a self-administered questionnaire based on the Global Health Professionals Student Survey and its additional modules. RESULTS:: The study sample comprised 556 students. The level of agreement with the World Health Organization recommendations was high, except for the components "received smoking cessation training" and "raising taxes is effective to reduce the prevalence of smoking". Most of the students reported that they agree with banning tobacco product sales to minors (95%), believe that physicians are role models to their patients (84%), and believe that they should advise their patients to quit cigarette smoking (96%) and using other tobacco products (94%). Regarding smoking cessation methods, most of the students were found to know more about nicotine replacement therapy than about non-nicotine therapies (93% vs. 53%). Only 37% of the respondents were aware of the importance of educational antismoking materials, and only 31% reported that they believe in the effectiveness of encouraging their patients, during medical visits. In our sample, the prevalence of current cigarette smoking was 5.23%; however, 43.82% of the respondents reported having experimented with water-pipe tobacco smoking. CONCLUSIONS:: Our results revealed the need to emphasize to third-year medical students the importance of raising the prices of and taxes on tobacco products. We also need to make students aware of the dangers of experimenting with tobacco products other than cigarettes, particularly water-pipe tobacco smoking. OBJETIVO:: Determinar o grau de concordância com medidas eficazes de controle do tabaco recomendadas pela Organização Mundial da Saúde e avaliar as atitudes, o conhecimento e as crenças a respeito do tabagismo em alunos do terceiro ano de medicina da Faculdade de Medicina da Universidade de São Paulo, em São Paulo (SP). MÉTODOS:: Entre 2008 e 2012, todos os alunos do terceiro ano de medicina foram convidados a preencher um questionário autoaplicável baseado na Global Health Professions Student Survey e em seus módulos adicionais. RESULTADOS:: A amostra consistiu em 556 estudantes. O grau de concordância com as recomendações da Organização Mundial da Saúde foi alto, à exceção de "receberam treinamento a respeito de cessação do tabagismo" e "aumentar os impostos é uma medida eficaz para reduzir a prevalência do tabagismo". A maioria dos estudantes relatou que concorda com a proibição da venda de produtos do tabaco a menores de idade (95%), acredita que os médicos são modelos de comportamento para seus pacientes (84%) e acredita que deveriam aconselhar seus pacientes a parar de fumar cigarros (96%) e de usar outros produtos do tabaco (94%). No tocante aos métodos de cessação do tabagismo, observamos que a maioria dos estudantes sabe mais sobre terapia de reposição da nicotina do que sobre terapias não nicotínicas (93% vs. 53%). Apenas 37% dos participantes estavam cientes da importância de material educacional antitabagismo, e apenas 31% relataram que acreditam na eficácia de incentivar seus pacientes, durante as consultas médicas, a parar de fumar. Em nossa amostra, a prevalência de tabagismo atual foi de 5,23%; entretanto, 43,82% dos participantes relataram ter experimentado fumar tabaco com um narguilé. CONCLUSÕES:: Nossos resultados revelaram a necessidade de deixar claro para os alunos do terceiro ano de medicina o quão importante é aumentar os preços e impostos dos produtos do tabaco. É também preciso conscientizar os alunos dos perigos de experimentar outros produtos do tabaco que não os cigarros, particularmente o narguilé.


Assuntos
Conhecimentos, Atitudes e Prática em Saúde , Abandono do Hábito de Fumar/métodos , Prevenção do Hábito de Fumar , Fumar/epidemiologia , Estudantes de Medicina/estatística & dados numéricos , Tabagismo/prevenção & controle , Adulto , Brasil/epidemiologia , Feminino , Humanos , Masculino , Prevalência , Autorrelato , Distribuição por Sexo , Fatores Sexuais , Fatores de Tempo , Adulto Jovem
3.
J. bras. pneumol ; 43(3): 202-207, May-June 2017. tab
Artigo em Inglês | LILACS | ID: biblio-893831

RESUMO

ABSTRACT Objective: To determine the level of agreement with effective tobacco control measures recommended by the World Health Organization and to assess the attitudes toward, knowledge of, and beliefs regarding smoking among third-year medical students at University of São Paulo School of Medicine, located in the city of São Paulo, Brazil. Methods: Between 2008 and 2012, all third-year medical students were invited to complete a self-administered questionnaire based on the Global Health Professionals Student Survey and its additional modules. Results: The study sample comprised 556 students. The level of agreement with the World Health Organization recommendations was high, except for the components "received smoking cessation training" and "raising taxes is effective to reduce the prevalence of smoking". Most of the students reported that they agree with banning tobacco product sales to minors (95%), believe that physicians are role models to their patients (84%), and believe that they should advise their patients to quit cigarette smoking (96%) and using other tobacco products (94%). Regarding smoking cessation methods, most of the students were found to know more about nicotine replacement therapy than about non-nicotine therapies (93% vs. 53%). Only 37% of the respondents were aware of the importance of educational antismoking materials, and only 31% reported that they believe in the effectiveness of encouraging their patients, during medical visits. In our sample, the prevalence of current cigarette smoking was 5.23%; however, 43.82% of the respondents reported having experimented with water-pipe tobacco smoking. Conclusions: Our results revealed the need to emphasize to third-year medical students the importance of raising the prices of and taxes on tobacco products. We also need to make students aware of the dangers of experimenting with tobacco products other than cigarettes, particularly water-pipe tobacco smoking.


RESUMO Objetivo: Determinar o grau de concordância com medidas eficazes de controle do tabaco recomendadas pela Organização Mundial da Saúde e avaliar as atitudes, o conhecimento e as crenças a respeito do tabagismo em alunos do terceiro ano de medicina da Faculdade de Medicina da Universidade de São Paulo, em São Paulo (SP). Métodos: Entre 2008 e 2012, todos os alunos do terceiro ano de medicina foram convidados a preencher um questionário autoaplicável baseado na Global Health Professions Student Survey e em seus módulos adicionais. Resultados: A amostra consistiu em 556 estudantes. O grau de concordância com as recomendações da Organização Mundial da Saúde foi alto, à exceção de "receberam treinamento a respeito de cessação do tabagismo" e "aumentar os impostos é uma medida eficaz para reduzir a prevalência do tabagismo". A maioria dos estudantes relatou que concorda com a proibição da venda de produtos do tabaco a menores de idade (95%), acredita que os médicos são modelos de comportamento para seus pacientes (84%) e acredita que deveriam aconselhar seus pacientes a parar de fumar cigarros (96%) e de usar outros produtos do tabaco (94%). No tocante aos métodos de cessação do tabagismo, observamos que a maioria dos estudantes sabe mais sobre terapia de reposição da nicotina do que sobre terapias não nicotínicas (93% vs. 53%). Apenas 37% dos participantes estavam cientes da importância de material educacional antitabagismo, e apenas 31% relataram que acreditam na eficácia de incentivar seus pacientes, durante as consultas médicas, a parar de fumar. Em nossa amostra, a prevalência de tabagismo atual foi de 5,23%; entretanto, 43,82% dos participantes relataram ter experimentado fumar tabaco com um narguilé. Conclusões: Nossos resultados revelaram a necessidade de deixar claro para os alunos do terceiro ano de medicina o quão importante é aumentar os preços e impostos dos produtos do tabaco. É também preciso conscientizar os alunos dos perigos de experimentar outros produtos do tabaco que não os cigarros, particularmente o narguilé.


Assuntos
Humanos , Masculino , Feminino , Adulto , Adulto Jovem , Conhecimentos, Atitudes e Prática em Saúde , Abandono do Hábito de Fumar/métodos , Prevenção do Hábito de Fumar , Fumar/epidemiologia , Estudantes de Medicina/estatística & dados numéricos , Tabagismo/prevenção & controle , Brasil/epidemiologia , Prevalência , Autorrelato , Distribuição por Sexo , Fatores Sexuais , Fatores de Tempo
4.
J Bras Pneumol ; 40(2): 102-10, 2014.
Artigo em Inglês, Português | MEDLINE | ID: mdl-24831393

RESUMO

OBJECTIVE: Water-pipe tobacco smoking is becoming increasingly more common among young people. The objective of this study was to estimate the prevalence of the use of water pipes and other forms of tobacco use, including cigarette smoking, among medical students, as well as to examine the attitudes, beliefs, and knowledge of those students regarding this issue. METHODS: We administered a questionnaire to students enrolled in the University of São Paulo School of Medicine, in São Paulo, Brazil. The respondents were evaluated in their third and sixth years of medical school, between 2008 and 2013. Comparisons were drawn between the two years. RESULTS: We evaluated 586 completed questionnaires. Overall, the prevalence of current cigarette smokers was low, with a decline among males (9.78% vs. 5.26%) and an increase among females (1.43% vs. 2.65%) in the 3rd and 6th year, respectively. All respondents believed that health professionals should advise patients to quit smoking. However, few of the medical students who smoked received physician advice to quit. Experimentation with other forms of tobacco use was more common among males (p<0.0001). Despite their knowledge of its harmful effects, students experimented with water-pipe tobacco smoking in high proportions (47.32% and 46.75% of the third- and sixth-year students, respectively). CONCLUSIONS: The prevalence of experimentation with water-pipe tobacco smoking and other forms of tobacco use is high among aspiring physicians. Our findings highlight the need for better preventive education programs at medical schools, not only to protect the health of aspiring physicians but also to help them meet the challenge posed by this new epidemic.


Assuntos
Atitude Frente a Saúde , Prevenção do Hábito de Fumar , Fumar/epidemiologia , Estudantes de Medicina/estatística & dados numéricos , Transtornos Relacionados ao Uso de Substâncias/epidemiologia , Transtornos Relacionados ao Uso de Substâncias/prevenção & controle , Adulto , Brasil/epidemiologia , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Masculino , Prevalência , Fatores Sexuais , Inquéritos e Questionários , Produtos do Tabaco/classificação , Universidades , Adulto Jovem
5.
J. bras. pneumol ; 40(2): 102-110, Mar-Apr/2014. tab, graf
Artigo em Inglês | LILACS | ID: lil-709767

RESUMO

OBJECTIVE: Water-pipe tobacco smoking is becoming increasingly more common among young people. The objective of this study was to estimate the prevalence of the use of water pipes and other forms of tobacco use, including cigarette smoking, among medical students, as well as to examine the attitudes, beliefs, and knowledge of those students regarding this issue. METHODS: We administered a questionnaire to students enrolled in the University of São Paulo School of Medicine, in São Paulo, Brazil. The respondents were evaluated in their third and sixth years of medical school, between 2008 and 2013. Comparisons were drawn between the two years. RESULTS: We evaluated 586 completed questionnaires. Overall, the prevalence of current cigarette smokers was low, with a decline among males (9.78% vs. 5.26%) and an increase among females (1.43% vs. 2.65%) in the 3rd and 6th year, respectively. All respondents believed that health professionals should advise patients to quit smoking. However, few of the medical students who smoked received physician advice to quit. Experimentation with other forms of tobacco use was more common among males (p<0.0001). Despite their knowledge of its harmful effects, students experimented with water-pipe tobacco smoking in high proportions (47.32% and 46.75% of the third- and sixth-year students, respectively). CONCLUSIONS: The prevalence of experimentation with water-pipe tobacco smoking and other forms of tobacco use is high among aspiring physicians. Our findings highlight the need for better preventive education programs at medical schools, not only to protect the health of aspiring physicians but also to help them meet the challenge posed by this new epidemic. .


OBJETIVO: O fumo de narguilé com tabaco está aumentando entre os jovens. O objetivo deste trabalho foi estimar a prevalência do uso de narguilé e outras formas de consumo de tabaco, incluindo o fumo de cigarros, entre estudantes de medicina, assim como as atitudes, crenças e conhecimento desses alunos sobre esse assunto. MÉTODOS: Um questionário foi aplicado aos estudantes da Faculdade de Medicina da Universidade de São Paulo. Os entrevistados eram alunos de terceiro e sexto anos entre 2008 e 2013. As respostas foram comparadas entre os dois anos de graduação. RESULTADOS: 586 estudantes responderam ao questionário. A prevalência de fumantes foi baixa, com um declínio entre os homens (9,78% contra 5,26%) e um aumento no sexo feminino (1,43% contra 2,65%) no 3º e 6º ano, respectivamente. Todos os entrevistados acreditavam que profissionais de saúde devem aconselhar os pacientes a parar de fumar. No entanto, a maioria dos estudantes de medicina fumantes não recebeu aconselhamento médico para deixar de fumar. A experimentação de outros produtos derivados do tabaco foi maior entre os homens (p < 0.0001). Apesar do conhecimento de seus efeitos nocivos à saúde, a experimentação de narguilé foi alta (47,32% e 46,75% entre alunos do terceiro e sexto anos, respectivamente. CONCLUSÕES: A prevalência da experimentação de narguilé com tabaco e de outras formas de uso de tabaco é alta entre os futuros médicos. Nossos achados enfatizam a necessidade de melhores programas de educação preventiva em universidades médicas para proteger a saúde dos futuros médicos e para ajudá-los a enfrentar esse novo desafio epidêmico. .


Assuntos
Adulto , Feminino , Humanos , Masculino , Adulto Jovem , Atitude Frente a Saúde , Fumar/epidemiologia , Fumar/prevenção & controle , Estudantes de Medicina/estatística & dados numéricos , Transtornos Relacionados ao Uso de Substâncias/epidemiologia , Transtornos Relacionados ao Uso de Substâncias/prevenção & controle , Brasil/epidemiologia , Conhecimentos, Atitudes e Prática em Saúde , Prevalência , Fatores Sexuais , Inquéritos e Questionários , Produtos do Tabaco/classificação , Universidades
6.
Arq Bras Cardiol ; 99(6): e184-90, 2012 Dec.
Artigo em Inglês, Português | MEDLINE | ID: mdl-23337994

RESUMO

The topic of tobacco smoking, in its several aspects, has been receiving increasing attention among researchers over the past few years, which has been reflected in more data and more solid scientific literature on the subject in national journals. This article aims to review the studies that focused on smoking published between January 2010 and June 2012, in Arquivos Brasileiros de Cardiologia (Brazilian Archives of Cardiology), Brazilian Journal of Medical and Biological Research, Clinics (Sao Paulo), Jornal Brasileiro de Pneumologia (Brazilian Journal of Pulmonology), Revista da Associação Médica Brasileira (Journal of the Brazilian Medical Association) and Revista Brasileira de Cirurgia Cardiovascular (Brazilian Journal of Cardiovascular Surgery). During the aforementioned period 58 articles were published, 52 of which were original ones, addressing several aspects of smoking, such as effects on health, epidemiology, cessation and experimental studies.


Assuntos
Bibliometria , Pesquisa Biomédica/estatística & dados numéricos , Publicações Periódicas como Assunto/estatística & dados numéricos , Fumar , Brasil/epidemiologia , Humanos , Fumar/efeitos adversos , Fumar/epidemiologia , /efeitos adversos
7.
J. bras. pneumol ; 37(6): 817-822, nov.-dez. 2011. ilus
Artigo em Português | LILACS | ID: lil-610916

RESUMO

Os sarcomas de artéria pulmonar são tumores raros e de difícil diagnóstico, simulando frequentemente o tromboembolismo pulmonar crônico. Relatamos dois casos de pacientes do sexo feminino com quadro clínico de dispneia e massas pulmonares associadas a falhas de enchimento na artéria pulmonar em angiotomografia de tórax. A tomografia por emissão de pósitrons com 18F fluordesoxiglicose mostrou hipercaptação das respectivas lesões. O sarcoma de artéria pulmonar foi confirmado posteriormente por exame anatomopatológico. Ressaltamos a importância do uso desse tipo de tomografia como exame não invasivo no auxílio diagnóstico desses tumores.


Pulmonary artery sarcomas are rare, difficult-to-diagnose tumors that frequently mimic chronic pulmonary thromboembolism. We report the cases of two female patients with clinical signs of dyspnea and lung masses associated with pulmonary artery filling defects on chest CT angiography. We performed 18F-fluorodeoxyglucose positron emission tomography, which revealed increased radiotracer uptake in those lesions. Pulmonary artery sarcoma was subsequently confirmed by anatomopathological examination. We emphasize the importance of this type of tomography as a noninvasive method for the diagnosis of these tumors.


Assuntos
Idoso , Feminino , Humanos , Pessoa de Meia-Idade , Tomografia por Emissão de Pósitrons/métodos , Artéria Pulmonar , Compostos Radiofarmacêuticos , Sarcoma , Neoplasias Vasculares , Doença Crônica , Diagnóstico Diferencial , Embolia Pulmonar/diagnóstico , Neoplasias Vasculares/patologia
8.
J Bras Pneumol ; 37(1): 118-28, 2011.
Artigo em Inglês, Português | MEDLINE | ID: mdl-21390440

RESUMO

Smoking among women has drawn increasing attention because of the increase (or less pronounced decrease) in its prevalence when compared with that observed for men, as well as because of the specific effects that smoking has on women's health. For the 2010 "World No Tobacco Day", the World Health Organization chose the theme "Gender and tobacco with an emphasis on marketing to women", with the aim of encouraging policies to combat marketing strategies employed by the tobacco industry and to curb the epidemic of smoking among women. In this article, we discuss the characteristics of smoking among women, addressing factors such as smoking prevalence, nicotine dependence, the role of the tobacco industry, health risks, approaches to smoking cessation, treatment strategies, and prevention measures.


Assuntos
Fumar/epidemiologia , Tabagismo/epidemiologia , Distribuição por Idade , Feminino , Promoção da Saúde , Humanos , Marketing , Prevalência , Fatores de Risco , Fatores Sexuais , Prevenção do Hábito de Fumar , Indústria do Tabaco , Tabagismo/etiologia , Tabagismo/prevenção & controle
9.
Clinics (Sao Paulo) ; 66(1): 65-71, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21437438

RESUMO

OBJECTIVE: To evaluate the effectiveness of nicotine replacement therapy (NRT), bupropion, nortriptyline and combination therapy and describe factors associated with treatment success. INTRODUCTION: Clinical trials clearly demonstrate the efficacy of pharmacotherapy in smoking cessation. However, it is only after its use in real-life settings that clinical effectiveness and limitations of a treatment are fully known. METHODS: Patients attended a four-session cognitive-behavioral program and received medicines free of charge. Abstinence from smoking was assessed at each visit. RESULTS: A total of 868 smokers (68.8% women) were included. Their mean age was 49.6 years; the amount smoked was 25 cigarettes/day and the Fagerströ m Score was 6.6. Abstinence rates after 6 months and 1 year were 36.5% and 33.6%. In univariate analysis, male gender, age (>50), higher number of cigarettes smoked, cardiovascular comorbidities, longer interval from the last cigarette and combined treatment of nortriptyline plus NRT were predictive of abstinence, while neuropsychiatric comorbidities and the answer ''yes'' to the question ''Do you smoke more often during the first hours after waking'' were correlated with failure. In a multivariate model, predictors of abstinence were neuropsychiatric comorbidities, the answer ''yes'' to the question ''Do you smoke more often during the first hours after waking'' and combined treatment of nortriptyline plus NRT. Male gender and a longer period from the last cigarette were correlated with lower abstinence rate. CONCLUSION: Satisfactory success rates were obtained in a teaching hospital. Factors such as age, daily cigarette consumption, number of pack-years and dependency score were not reliable markers of abstinence. The combination nortriptyline+NRT was independently associated with higher abstinence rates.


Assuntos
Abandono do Hábito de Fumar/métodos , Fumar/tratamento farmacológico , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Bupropiona/uso terapêutico , Terapia Combinada , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Nicotina/uso terapêutico , Nortriptilina/uso terapêutico , Estudos Retrospectivos , Fatores Sexuais , Fatores de Tempo , Resultado do Tratamento , Adulto Jovem
10.
J. bras. pneumol ; 37(1): 118-128, jan.-fev. 2011. tab
Artigo em Português | LILACS | ID: lil-576120

RESUMO

O tabagismo entre as mulheres tem cada vez mais merecido destaque devido ao aumento (ou da redução menos acentuada) de sua prevalência em comparação com aquela dos homens, bem como devido a especificidades dos efeitos do tabagismo na saúde da mulher. Em 2010, a Organização Mundial da Saúde elegeu para o "Dia Mundial sem Tabaco" o tema "Gênero e tabaco com ênfase na propaganda voltada para a mulher", com o objetivo de estimular políticas de combate às estratégias de marketing da indústria do tabaco e conter a epidemia de tabagismo entre as mulheres. O presente artigo discorre sobre as características do tabagismo na mulher, abordando fatores como prevalência, dependência, a atuação da indústria, riscos à saúde, abordagens à cessação do tabagismo e estratégias de tratamento e prevenção.


Smoking among women has drawn increasing attention because of the increase (or less pronounced decrease) in its prevalence when compared with that observed for men, as well as because of the specific effects that smoking has on women's health. For the 2010 "World No Tobacco Day", the World Health Organization chose the theme "Gender and tobacco with an emphasis on marketing to women", with the aim of encouraging policies to combat marketing strategies employed by the tobacco industry and to curb the epidemic of smoking among women. In this article, we discuss the characteristics of smoking among women, addressing factors such as smoking prevalence, nicotine dependence, the role of the tobacco industry, health risks, approaches to smoking cessation, treatment strategies, and prevention measures.


Assuntos
Feminino , Humanos , Fumar/epidemiologia , Tabagismo/epidemiologia , Distribuição por Idade , Promoção da Saúde , Marketing , Prevalência , Fatores de Risco , Fatores Sexuais , Fumar/prevenção & controle , Indústria do Tabaco , Tabagismo/etiologia , Tabagismo/prevenção & controle
11.
J Bras Pneumol ; 37(6): 817-22, 2011.
Artigo em Inglês, Português | MEDLINE | ID: mdl-22241041

RESUMO

Pulmonary artery sarcomas are rare, difficult-to-diagnose tumors that frequently mimic chronic pulmonary thromboembolism. We report the cases of two female patients with clinical signs of dyspnea and lung masses associated with pulmonary artery filling defects on chest CT angiography. We performed 18F-fluorodeoxyglucose positron emission tomography, which revealed increased radiotracer uptake in those lesions. Pulmonary artery sarcoma was subsequently confirmed by anatomopathological examination. We emphasize the importance of this type of tomography as a noninvasive method for the diagnosis of these tumors.


Assuntos
Fluordesoxiglucose F18 , Tomografia por Emissão de Pósitrons/métodos , Artéria Pulmonar/diagnóstico por imagem , Compostos Radiofarmacêuticos , Sarcoma/diagnóstico por imagem , Neoplasias Vasculares/diagnóstico por imagem , Idoso , Doença Crônica , Diagnóstico Diferencial , Feminino , Humanos , Pessoa de Meia-Idade , Embolia Pulmonar/diagnóstico , Neoplasias Vasculares/patologia
12.
Clinics ; 66(1): 65-71, 2011. ilus, tab
Artigo em Inglês | LILACS | ID: lil-578598

RESUMO

OBJECTIVE: To evaluate the effectiveness of nicotine replacement therapy (NRT), bupropion, nortriptyline and combination therapy and describe factors associated with treatment success. INTRODUCTION: Clinical trials clearly demonstrate the efficacy of pharmacotherapy in smoking cessation. However, it is only after its use in real-life settings that clinical effectiveness and limitations of a treatment are fully known. METHODS: Patients attended a four-session cognitive-behavioral program and received medicines free of charge. Abstinence from smoking was assessed at each visit. RESULTS: A total of 868 smokers (68.8 percent women) were included. Their mean age was 49.6 years; the amount smoked was 25 cigarettes/day and the Fagerströ m Score was 6.6. Abstinence rates after 6 months and 1 year were 36.5 percent and 33.6 percent. In univariate analysis, male gender, age (>50), higher number of cigarettes smoked, cardiovascular comorbidities, longer interval from the last cigarette and combined treatment of nortriptyline plus NRT were predictive of abstinence, while neuropsychiatric comorbidities and the answer ''yes'' to the question ''Do you smoke more often during the first hours after waking'' were correlated with failure. In a multivariate model, predictors of abstinence were neuropsychiatric comorbidities, the answer ''yes'' to the question ''Do you smoke more often during the first hours after waking'' and combined treatment of nortriptyline plus NRT. Male gender and a longer period from the last cigarette were correlated with lower abstinence rate. CONCLUSION: Satisfactory success rates were obtained in a teaching hospital. Factors such as age, daily cigarette consumption, number of pack-years and dependency score were not reliable markers of abstinence. The combination nortriptyline+NRT was independently associated with higher abstinence rates.


Assuntos
Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Abandono do Hábito de Fumar/métodos , Fumar/tratamento farmacológico , Fatores Etários , Bupropiona/uso terapêutico , Terapia Combinada , Seguimentos , Análise Multivariada , Nicotina/uso terapêutico , Nortriptilina/uso terapêutico , Estudos Retrospectivos , Fatores Sexuais , Fatores de Tempo , Resultado do Tratamento
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